Here it is: DNA sequences reveal Ebola’s spread and mutation!

Thursday, August 28, 2014
By Paul Martin

Investmentwatchblog.com
August 28th, 2014

DNA sequences reveal Ebola’s spread and mutation

The virus was not recognized in West Africa until March of this year, however, when the first case was confirmed in Guinea. Gire said the West African epidemic likely began after a single zoonotic event — in other words, transmission of the virus from an animal to a person.

Gire said his study shows that more than 300 mutations have occurred since Ebola began infecting people in Sierra Leone. Every time a virus passes from one person to another, it is likely some mutations will occur, though not all of them will be passed down.

http://www.mykawartha.com/news-story/4804151-dna-sequences-reveal-ebola-s-spread-and-mutation/

Published Online August 28 2014: Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

Phylogenetic comparison to all 20 genomes from earlier outbreaks suggests the 2014 West African virus likely spread from Middle Africa within the last decade. Rooting the phylogeny using divergence to other ebolavirus genomes is problematic (Fig. 2A and fig. S6) (6, 13). However, rooting the tree on the oldest outbreak reveals a strong correlation between sample date and root-to-tip distance, with a substitution rate of 8×10−4/site/year (Fig. 2B and fig. S7) (13). This suggests that the lineages of the three most recent outbreaks all diverged from a common ancestor at roughly the same time c. 2004 (Fig. 2C and Fig. 3A), supporting the hypothesis that each outbreak represents an independent zoonotic event from the same genetically diverse viral population in its natural reservoir.

http://www.sciencemag.org/content/early/2014/08/27/science.1259657.full

Read more at http://investmentwatchblog.com/here-it-is-dna-sequences-reveal-ebolas-spread-and-mutation/#y3LeyCLkWICEsplg.99

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