We’ve already identified three natural molecules that inhibit coronavirus replication in the body… and they don’t come from Big Pharma
by: Mike Adams
NaturalNews.com
Monday, February 10, 2020
While the world of the brainwashed masses are waiting for Big Pharma to save them from the coronavirus pandemic with a drug or a vaccine, we’ve been researching molecules from nature that are known to inhibit coronavirus replication in the body.
So far, we’ve already identified three natural molecules. One of them is abundantly found in a common spice (that’s really orange), and the two other molecules are more rare, but still available from the world of nature.
These molecules target the coronavirus 3 chymotrypsin-like protease (3CL) enzyme, which is well known as a molecular target when searching for anticoronavirus inhibitors.
For example, this study published in BMC Structural Biology discusses the role of 3CL and why inhibiting this enzymatic function is a valid method for blocking coronavirus replication:
The 3CLpro has been validated as an effective drug target in several studies and has even been termed “the Achilles’ heel of coronaviruses” [8] making it an ideal target for the identification of novel lead compounds.
The coronavirus 3 chymotrypsin-like protease (3CLpro) is a validated target in the design of potential anticoronavirus inhibitors. The high degree of homology within the protease’s active site and substrate conservation supports the identification of broad spectrum lead compounds. A previous study identified the compound ML188, also termed 16R, as an inhibitor of the Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) 3CLpro. This study will detail the generation of a homology model of the 3CLpro of the human coronavirus OC43 and determine the potential of 16R to form a broad-spectrum lead compound.
It turns out there was a huge wave of research into SARS following that outbreak from a few years ago. Scientists studied numerous botanicals, phytochemicals and food isolates that might show promise in halting SARS, which is also a coronavirus.
Many pharmaceuticals were tested as well, and because of that research, certain drugs are also documented to combat SARS. They are very likely to high efficacy against the nCoV coronavirus as well. Niclosamide, a prescription medication used to treat tapeworms, is one of the prescription drugs that should be immediately studied for treating coronavirus infections.
Search for “inhibition of SARS-CoV 3CL protease”
The Rest…HERE
